COPD is a chronic lung disease that includes chronic bronchitis, emphysema, or both. COPD affects the lungs and causes reduced airflow, which makes it hard to breathe. It is also progressive, which means it worsens over time.
This study will assess product use behaviors, biomarkers of exposure, subjective effects and safety of an electronic nicotine delivery system (ENDS) as compared to smoking your usual brand of cigarettes over 8-weeks.
The purpose of this study is to look at a drug called cytisinicline to see how effective it is at enabling people to quit smoking as compared to a placebo.
The purpose of this study is to assess the safety and effectiveness of 3 doses of the investigational drug as compared to a placebo.